Treningsforum

Kosthold => Kosthold og Ernæring => Emne startet av: Beefcake på 22. mai 2007, 13:27



Tittel: 1 måltid om dagen (periodisk fasta)
Skrevet av: Beefcake22. mai 2007, 13:27
Ny studie på 1 måltid vs 3 måltider om dagen. Samma kaloriintag.


---------------

A controlled trial of reduced meal frequency without caloric restriction in healthy, normal-weight, middle-aged adults

American Journal of Clinical Nutrition, Vol. 85, No. 4, 981-988, April 2007

Background:Although consumption of 3 meals/d is the most common pattern of eating in industrialized countries, a scientific rationale for this meal frequency with respect to optimal health is lacking. A diet with less meal frequency can improve the health and extend the lifespan of laboratory animals, but its effect on humans has never been tested.

Objective:A pilot study was conducted to establish the effects of a reduced-meal-frequency diet on health indicators in healthy, normal-weight adults.

Design:The study was a randomized crossover design with two 8-wk treatment periods. During the treatment periods, subjects consumed all of the calories needed for weight maintenance in either 3 meals/d or 1 meal/d.

Results:Subjects who completed the study maintained their body weight within 2 kg of their initial weight throughout the 6-mo period. There were no significant effects of meal frequency on heart rate, body temperature, or most of the blood variables measured. However, when consuming 1 meal/d, subjects had a significant increase in hunger; a significant modification of body composition, including reductions in fat mass; significant increases in blood pressure and in total, LDL-, and HDL-cholesterol concentrations; and a significant decrease in concentrations of cortisol.

Conclusions:Normal-weight subjects are able to comply with a 1 meal/d diet. When meal frequency is decreased without a reduction in overall calorie intake, modest changes occur in body composition, some cardiovascular disease risk factors, and hematologic variables. Diurnal variations may affect outcomes.

http://www.ajcn.org/cgi/content/abstract/85/4/981 (http://www.ajcn.org/cgi/content/abstract/85/4/981)


Tittel: Sv: 1 måltid om dagen.
Skrevet av: DanielF22. mai 2007, 13:37
Spennende studie.

Men og holde seg til ett måltid om dagen, hadde blitt utrolig vanskelig.


Tittel: Sv: 1 måltid om dagen.
Skrevet av: Beefcake22. mai 2007, 13:46
Spennende studie.

Men og holde seg til ett måltid om dagen, hadde blitt utrolig vanskelig.

Man vänjer sig :)

Men en som i stort sett bara åt en monstermåltid (5000 kcal+) sent på kvällen, och på dagen bara levde på vatten, juice och tillskott var Serge Nubret (möjligt att han gör det än idag, det vet jag inte.. Men han är i alla fall fortfarande i väldigt bra form. Här är bilder på honom 65 år gammal (http://www.treningsforum.no/forum/index.php?topic=56365.msg782696#msg782696))

Serge Nubret:
(http://digilander.libero.it/sergenubret/nub34.jpg)


Tittel: Sv: 1 måltid om dagen.
Skrevet av: kennyo22. mai 2007, 14:25
Tror ikke jeg hadde vært til å leve med om jeg skulle spist bare en gang om dagen. Merker at jeg blir mer irritabel og ukonsentrert hvis det er lenge siden jeg har spist. Mulig kroppen vil venne seg til det etterhvert, men med tanke på både komforten (unngå sult) og at det skal kunne gå an å snakke med meg, tror jeg det er best jeg fortsetter med flere måltider daglig.  ;) For alles del.  ;)


Tittel: Sv: 1 måltid om dagen.
Skrevet av: UpAndComming22. mai 2007, 14:28
Det er en vanesak faktisk, og et måltid om dagen betyr også at man må/bør ha en stor andel av maten fra fett. Da holder man også lenger. Det er en omstillingsprosess men overhodet ikke umulig.

Selv trives jeg best med 3-4 måltider for tiden.

Kan jo nevnes at det finnes undersøkelser om at også 3 måltider er bedre enn 5-6; altså ferre kan være bedre.


Tittel: Sv: 1 måltid om dagen.
Skrevet av: UpAndComming22. mai 2007, 14:32
Hei og hei!
Må komme med en rettelse, jeg! En meget sentral rettelse  ;)
Resultatene fra min hovedoppgave var faktisk mer "sjokkerende" (!) enn som så: for stikk i strid med all forventning, var det de som spiste 3 måltider pr dag som fikk best resultater i enkelte av styrke- og muskelutviklings resultatene!!!

Konklusjonen vår var at det ikke ser ut til å være av særlig avgjørende grad hvor ofte du spiser pr dag, så lenge du dekke totalt energi, karb- og proteinbehov. Men at det altså kan se ut som at å spise 3 ganger pr dag, kan være fordelaktig, fordi det gav statistisk bedre resultater i en del av testene våre.

Utfordringen for de fleste som vil prøve å følge disse resultatene, er som påpekt, å klare å få i seg all maten de trenger på bare 3 måltider...


Tittel: Sv: 1 måltid om dagen.
Skrevet av: kennyo22. mai 2007, 14:40
Det er en vanesak faktisk, og et måltid om dagen betyr også at man må/bør ha en stor andel av maten fra fett. Da holder man også lenger. Det er en omstillingsprosess men overhodet ikke umulig.

Selv trives jeg best med 3-4 måltider for tiden.

Kan jo nevnes at det finnes undersøkelser om at også 3 måltider er bedre enn 5-6; altså ferre kan være bedre.

Ja, jeg har skummet gjennom den ENORME tråden om mellommåltid der Beefcake og Baahh kom med mange gode innlegg. Mye bra lesestoff der, dog tror jeg jeg står fast på flere måltider om dagen. Selv om jeg sikkert kan venne meg til et enkelt stort, frykter jeg at "tilvenningsperioden" fører til samlivsbrudd.  ;D


Tittel: Sv: 1 måltid om dagen.
Skrevet av: UpAndComming22. mai 2007, 14:42
Greit å legge linken dit også vel :

http://www.treningsforum.no/forum/index.php?topic=51143.0 (http://www.treningsforum.no/forum/index.php?topic=51143.0)


Tittel: Sv: 1 måltid om dagen.
Skrevet av: kennyo22. mai 2007, 14:45
....du kom meg i forkjøpet, skulle editere med link...  ::blush::


Tittel: Sv: 1 måltid om dagen.
Skrevet av: Beefcake22. mai 2007, 20:37
Det er en vanesak faktisk, og et måltid om dagen betyr også at man må/bør ha en stor andel av maten fra fett. Da holder man også lenger. Det er en omstillingsprosess men overhodet ikke umulig.

Selv trives jeg best med 3-4 måltider for tiden.

Kan jo nevnes at det finnes undersøkelser om at også 3 måltider er bedre enn 5-6; altså ferre kan være bedre.

Överväger att pröva med 3 måltider själv i en period, med den största måltiden på kvällen efter träningen. Protein/karboshakerna före och efter träning behåller jag dock som vanligt.

Appropå en stor måltid sent på kvällen så är den här tråden aktuell:
http://www.treningsforum.no/forum/index.php?topic=55556.0 (http://www.treningsforum.no/forum/index.php?topic=55556.0)

 ::food:: ::food:: ::food:: ::food:: ::food:: ::food:: ::food:: ::food:: ::food:: ::food:: ::food:: ::food:: ::food:: ::food:: ::food::


Tittel: Sv: 1 måltid om dagen.
Skrevet av: Beefcake15. juni 2007, 08:44
Intressant JohnBlond!

Här är en relevant studie:
Åtta friska och sunda danska 25-åriga män fastade varannan dag från kl 22 på kvällen till kl 18 följande dag i 14 dagar (de åt alltså hela dagsbehovet av kalorier inom en 4-timmars period från 18-22 de dagarna de fastade, de andra dagarna åt de normalt). Ingen förändring i vikt observerades. De heller tappade varken muskler eller fett, men däremot fick de ökad insulinsensitivitet.

Ökad insulinsensitivitet är bra då det gör kroppen mer effektiv på att ta hand om näringen. Har man dålig insulinsensitivitet blir muskelcellerna sämre på att reagera på insulin (som frigörs när man äter) så energi (mat) som tillförs kroppen uppfattas som överflödig och inlagras i större grad i som bukfett eller underhudsfett. Alltså ökad insulinsensitivitet = mer muskler, mindre fett.

Detta stöder resultaten i den första studien i tråden, där de under en 8-veckors period ökade i muskelmassa och minskade i fett när de åt hela sitt kaloribehov i en måltid om dagen.


Effect of intermittent fasting and refeeding on insulin action in healthy men
J Appl Physiol. 2005 Dec;99(6):2128-36. Epub 2005 Jul 28

"Insulin resistance is currently a major health problem. This may be because of a marked decrease in daily physical activity during recent decades combined with constant food abundance. This lifestyle collides with our genome, which was most likely selected in the late Paleolithic era (50,000–10,000 BC) by criteria that favored survival in an environment characterized by fluctuations between periods of feast and famine. The theory of thrifty genes states that these fluctuations are required for optimal metabolic function. We mimicked the fluctuations in eight healthy young men [25.0 ± 0.1 yr (mean ± SE); body mass index: 25.7 ± 0.4 kg/m2] by subjecting them to intermittent fasting every second day for 20 h for 15 days. Euglycemic hyperinsulinemic (40 mU·min–1·m–2) clamps were performed before and after the intervention period. Subjects maintained body weight (86.4 ± 2.3 kg; coefficient of variation: 0.8 ± 0.1%). Plasma free fatty acid and -hydroxybutyrate concentrations were 347 ± 18 and 0.06 ± 0.02 mM, respectively, after overnight fast but increased (P < 0.05) to 423 ± 86 and 0.10 ± 0.04 mM after 20-h fasting, confirming that the subjects were fasting. Insulin-mediated whole body glucose uptake rates increased from 6.3 ± 0.6 to 7.3 ± 0.3 mg·kg–1·min–1 (P = 0.03), and insulin-induced inhibition of adipose tissue lipolysis was more prominent after than before the intervention (P = 0.05). After the 20-h fasting periods, plasma adiponectin was increased compared with the basal levels before and after the intervention (5,922 ± 991 vs. 3,860 ± 784 ng/ml, P = 0.02). This experiment is the first in humans to show that intermittent fasting increases insulin-mediated glucose uptake rates, and the findings are compatible with the thrifty gene concept."

http://jap.physiology.org/cgi/content/full/99/6/2128 (http://jap.physiology.org/cgi/content/full/99/6/2128")


Tittel: Sv: 1 måltid om dagen.
Skrevet av: Mihoe15. juni 2007, 09:34
Jeg har lest litt i disse trådene om få måltider om dagen.

Selv vet jeg at jeg aldri hadde fikset det fordi blodsukkeret mitt hadde blitt for lavt. Hadde jeg gått rundt med konstant lavt blodsukker hadde jeg ikke klart å jobbe, tenke eller trene og da hadde det vært liten vits i noe som helst.

Dessuten er det ikke et eller annet med at glukogenlagrene bare klarer å lage en viss mengde energi (2000 kcal eller noe) og at resten av energien du får i deg i et stort måltid vil lagres i fettdepoene?

I min diett er energifordelingen ca. 15-30% fra protein, 60-85% fra fett og 0-10% fra karbohydrater.

Vil et slikt kosthold, med denne sammensetningen, gi nok av de næringsstoffene man trenger?


Tittel: Sv: 1 måltid om dagen.
Skrevet av: UpAndComming15. juni 2007, 09:40
For å svare på det, så vil du absolutt gjøre det gitt at du spiser riktig. Et slikt kosthold vil typisk bestå av mye kjøtt, egg, smør, olje og da får du i deg mer enn rikelig av hva du trenger. Det eneste du kanskje kan ta en titt på er noen få mineraler. Merk også at du bør spise kjøttet "så rått som mulig" dersom du ikke får i deg noe c-vitaminer fra andre kilder.

Dette du snakker om vedr. blodsukker og at det blir for lavt så er ikke det noe problem. Du må nesten prøve selv, men jeg trodde også det - helt til jeg prøvde dette kostholdet.


Tittel: Sv: 1 måltid om dagen.
Skrevet av: Mihoe15. juni 2007, 09:50
For å svare på det, så vil du absolutt gjøre det gitt at du spiser riktig. Et slikt kosthold vil typisk bestå av mye kjøtt, egg, smør, olje og da får du i deg mer enn rikelig av hva du trenger. Det eneste du kanskje kan ta en titt på er noen få mineraler. Merk også at du bør spise kjøttet "så rått som mulig" dersom du ikke får i deg noe c-vitaminer fra andre kilder.

Dette du snakker om vedr. blodsukker og at det blir for lavt så er ikke det noe problem. Du må nesten prøve selv, men jeg trodde også det - helt til jeg prøvde dette kostholdet.

Regner med at det var svar på mine "innsigelser".

Jeg tror kanskje et stikkord her vil være kjøtt. Selv har jeg ikke spist kjøtt på tjue år og jeg tror kanskje det ville gjort en slik spiseplan totalt umulig for meg. Kjøtt bruker vel relativt lang tid på å fordøyes og spiser du mye av det vil kanskje kroppen tilføres energi selv om det er lenge siden du spiste.

Når det gjelder et kosthold som i så stor grad henter energien sin fra fett som det Jon Blonds gjør ville jeg trodd det medførte mangler på en del vitaminer og annet fint som du kan hente fra grønnsaksriket.

Jeg har alltid vært relativt sensitiv i forhold til lavt blodsukker så jeg vet ikke om jeg vil prøve - selv om det må sies at jeg i perioder har levd på et lite og et stort måltid om dagen.

:)


Tittel: Sv: 1 måltid om dagen.
Skrevet av: Beefcake15. juni 2007, 10:00
Sitat fra: Mihoe

Selv vet jeg at jeg aldri hadde fikset det fordi blodsukkeret mitt hadde blitt for lavt. Hadde jeg gått rundt med konstant lavt blodsukker hadde jeg ikke klart å jobbe, tenke eller trene og da hadde det vært liten vits i noe som helst.

Blodsockret stabiliserar sig. Om det går länge mellan måltiderna börjar blodsockret bli lågt eftersom blodet inte får någon påfyllning av glukos från tunntarmscellerna (där maten du äter behandlas), detta triggar bukspottkörteln att utsöndra glukagon, och glukagonet påverkar levern och musklerna att släppa ut en del av det glukos de har lagrat (ca 50-100 g i levern och ca 3-500 g i musklerna) till blodet och voilà: blodsockret stabiliseras, och allt är frid och fröjd. Kroppen gillar att jämna ut saker och ting. :)


Sitat fra: Mihoe

Dessuten er det ikke et eller annet med at glukogenlagrene bare klarer å lage en viss mengde energi (2000 kcal eller noe) og at resten av energien du får i deg i et stort måltid vil lagres i fettdepoene?

Nope. All näring lagras ju för det första inte direkt in som muskelglykogen (där det ryms ca 3-500 g * 4 = 1500-2000 kcal som regel).

Allt fett du äter lagras in som fett (och där finns det gott om plats.. Fettcellerna rymmer ju hos en normal person kanske 50-100.000 kcal). Men det är inte så illa som det låter. Så länge du inte äter mer kalorier än du gör av med så förbränns lika mycket fett som lagras in.



Tittel: Sv: 1 måltid om dagen.
Skrevet av: Beefcake15. juni 2007, 10:45
Jeg tror kanskje et stikkord her vil være kjøtt. Selv har jeg ikke spist kjøtt på tjue år og jeg tror kanskje det ville gjort en slik spiseplan totalt umulig for meg. Kjøtt bruker vel relativt lang tid på å fordøyes og spiser du mye av det vil kanskje kroppen tilføres energi selv om det er lenge siden du spiste.

Mjo, men man måste ju inte ha mat i magen för att ha energi. Du har mer än nog lagrat främst som fett, men också som glykogen i muskler och lever.


Tittel: Sv: 1 måltid om dagen.
Skrevet av: Mihoe15. juni 2007, 11:51
Takk for gode svar Beefcake :)

Tviler på at en slik måte å spise på er noe for meg, men bra å ta liv av myter (eventuelt stille spørsmål ved vedtatte sanheter). Jeg er, i likhet med deg, for glad i mat.



Tittel: Sv: 1 måltid om dagen.
Skrevet av: Beefcake15. juni 2007, 12:01
Takk for gode svar Beefcake :)

Tviler på at en slik måte å spise på er noe for meg, men bra å ta liv av myter (eventuelt stille spørsmål ved vedtatte sanheter). Jeg er, i likhet med deg, for glad i mat.

Bare hyggelig :)

Nej, det passar ju förstås inte för alla. Jag äter inte en gång om dagen heller, utan snarare 2-3 ggr. Levde länge mot bättre vetande efter "ju fler måltider desto bättre", men det enda det egentligen ledde till var mer hål i tänderna... Trivs mycket bättre med att äta rejäla måltider istället för att gå och småäta hela tiden.


Tittel: Sv: 1 måltid om dagen.
Skrevet av: kriweb15. juni 2007, 12:23
Bare hyggelig :)

Nej, det passar ju förstås inte för alla. Jag äter inte en gång om dagen heller, utan snarare 2-3 ggr. Levde länge mot bättre vetande efter "ju fler måltider desto bättre", men det enda det egentligen ledde till var mer hål i tänderna... Trivs mycket bättre med att äta rejäla måltider istället för att gå och småäta hela tiden.

Off topic men.. kanskje en tur innom tannlegen en gang i året hadde hjulpet litt og  ::)


Tittel: Sv: 1 måltid om dagen.
Skrevet av: Beefcake15. juni 2007, 12:35
Off topic men.. kanskje en tur innom tannlegen en gang i året hadde hjulpet litt og  ::)

Ehum... ::)


Tittel: Sv: 1 måltid om dagen.
Skrevet av: Beefcake20. juni 2007, 17:43
Fasta gör dig (temporärt) smartare:

"Empty-Stomach Intelligence
By CHRISTOPHER SHEA
Published: December 10, 2006

Hunger makes the best sauce, goes the maxim. According to researchers at Yale Medical School, it may make quadratic equations and Kant’s categorical imperative go down easier too. The stimulation of hunger, the researchers announced in the March issue of Nature Neuroscience, causes mice to take in information more quickly, and to retain it better — basically, it makes them smarter. And that’s very likely to be true for humans as well.
 
A team led by Tamas Horvath, chairman of Yale’s comparative medicine program, had been analyzing the pathways followed in mouse brains by ghrelin, a hormone produced by the stomach lining, when the stomach is empty. To the scientists’ surprise, they found that ghrelin was binding to cells not just in the primitive part of the brain that registers hunger (the hypothalamus) but also in the region that plays a role in learning, memory and spatial analysis (the hippocampus).

The researchers then put mice injected with ghrelin and control mice through a maze and other intelligence tests. In each case, the biochemically “hungry” mice — mice infused with ghrelin — performed notably better than those with normal levels of the hormone. The finding was startling, but “it makes sense,” Horvath says. “When you are hungry, you need to focus your entire system on finding food in the environment.” In fact, some biologists believe that human intelligence itself evolved because it made early hominids more effective hunters, gathers and foragers.

Horvath says we can use the hormonal discoveries to our cognitive advantage. Facing the LSAT, a final exam or a half-day job interview? Go in mildly hungry, not carbo-loaded for endurance, and snack to maintain that edgy state. Such advice, applied on a national scale, might help save our schools. Since overweight kids have suppressed ghrelin levels, Horvath theorizes that perhaps the obesity epidemic has contributed to declining test scores and other American educational woes."


http://www.nytimes.com/2006/12/10/magazine/10section1C.t-1.html?ex=1323406800&en=06f62b1f071e37ff&ei=5090 (http://www.nytimes.com/2006/12/10/magazine/10section1C.t-1.html?ex=1323406800&en=06f62b1f071e37ff&ei=5090)


Tittel: Sv: 1 måltid om dagen.
Skrevet av: Beefcake22. juli 2007, 20:09
Intressant JohnBlond!

Tror en av nycklarna till ett långt liv stavas insulinsensitivitet.

Har man dålig insulinsensitivitet blir musklerna sämre på att reagera på insulin, vilket leder till två saker; dels att kroppen uppfattar mer av energin du får i dig via mat som överflödig och vill i högre grad lagra in den som fett, samt att kroppen utsöndrar mer insulin för att regulera blodsockret. Och ju mer insulin du utsöndrar genom livet, desto mer stress på insulin och IGF "signaling pathways" (1) med kortare livslängd, större risk för åldersrelaterade försämringar av kognitiva funktioner (minne, etc.), större risk för att drabbas av stroke, samt sjukdomar som Alzheimers, Parkinsons och Huntingtons.

Träning och ett sunt kosthåll (i betydningen att man begränsar först och främst mängden kalorier men även glykemiska belastningen) gör helt enkelt att du lever längre och friskare.

Om man är intresserad av att leva ett långt och friskt liv men samtidigt inte begränsa antalet kalorier man får i sig alltför mycket (svårt att bygga muskler då...) kan det vara en idé att glömma det här med att äta ofta och hellre följa ett upplägg med periodisk fasta. Studier visar att periodisk fasta (alltså t.ex. äta all mat för dagen inom en period av ett par timmar och fasta resten av dagen, eller fasta varannan dag) kan ha samma positiva effekter som kalorirestriktion, utan att man behöver begränsa antalet kalorier.

Periodisk fasta ökar insulinsensitiviteten (2).

Studier om periodisk fasta och livslängd, Alzheimers, etc (3,4,5,6,7).







1. "Single gene mutations that extend lifespan have drastically changed ageing research because they offer potential answers to the questions of why and how we age. Mutations that lower activity of the insulin and insulin-like growth factor signalling (IIS) pathways extend the lifespan of worms, flies and mice. It is possible, therefore, to learn about human ageing from the conserved features of these long-lived models. Here, we summarise the available data in this light.

Models of insulin signalling and longevity. Drug Discovery Today: Disease Models. Volume 2, Issue 4, Winter 2005, Pages 249-256



2. "Insulin resistance is currently a major health problem. This may be because of a marked decrease in daily physical activity during recent decades combined with constant food abundance. This lifestyle collides with our genome, which was most likely selected in the late Paleolithic era (50,000-10,000 BC) by criteria that favored survival in an environment characterized by fluctuations between periods of feast and famine. The theory of thrifty genes states that these fluctuations are required for optimal metabolic function. We mimicked the fluctuations in eight healthy young men [25.0 +/- 0.1 yr (mean +/- SE); body mass index: 25.7 +/- 0.4 kg/m(2)] by subjecting them to intermittent fasting every second day for 20 h for 15 days. Euglycemic hyperinsulinemic (40 mU.min(-1).m(-2)) clamps were performed before and after the intervention period. Subjects maintained body weight (86.4 +/- 2.3 kg; coefficient of variation: 0.8 +/- 0.1%). Plasma free fatty acid and beta-hydroxybutyrate concentrations were 347 +/- 18 and 0.06 +/- 0.02 mM, respectively, after overnight fast but increased (P < 0.05) to 423 +/- 86 and 0.10 +/- 0.04 mM after 20-h fasting, confirming that the subjects were fasting. Insulin-mediated whole body glucose uptake rates increased from 6.3 +/- 0.6 to 7.3 +/- 0.3 mg.kg(-1).min(-1) (P = 0.03), and insulin-induced inhibition of adipose tissue lipolysis was more prominent after than before the intervention (P = 0.05). After the 20-h fasting periods, plasma adiponectin was increased compared with the basal levels before and after the intervention (5,922 +/- 991 vs. 3,860 +/- 784 ng/ml, P = 0.02). This experiment is the first in humans to show that intermittent fasting increases insulin-mediated glucose uptake rates, and the findings are compatible with the thrifty gene concept."

Effect of intermittent fasting and refeeding on insulin action in healthy men. J Appl Physiol. 2005 Dec;99(6):2128-36. Epub 2005 Jul 28.



3. "We conclude that caloric restriction and intermittent fasting dietary regimens can ameliorate age-related deficits in cognitive function by mechanisms that may or may not be related to Abeta and tau pathologies."

Intermittent fasting and caloric restriction ameliorate age-related behavioral deficits in the triple-transgenic mouse model of Alzheimer's disease. Neurobiol Dis. 2007 Apr;26(1):212-20. Epub 2007 Jan 13.



4. "The vulnerability of the nervous system to advancing age is all too often manifest in neurodegenerative disorders such as Alzheimer's and Parkinson's diseases. In this review article we describe evidence suggesting that two dietary interventions, caloric restriction (CR) and intermittent fasting (IF), can prolong the health-span of the nervous system by impinging upon fundamental metabolic and cellular signaling pathways that regulate life-span. CR and IF affect energy and oxygen radical metabolism, and cellular stress response systems, in ways that protect neurons against genetic and environmental factors to which they would otherwise succumb during aging."

Caloric restriction and intermittent fasting: two potential diets for successful brain aging.
Ageing Res Rev. 2006 Aug;5(3):332-53. Epub 2006 Aug 8.



5. "Intermittent fasting (IF; reduced meal frequency) and caloric restriction (CR) extend lifespan and increase resistance to age-related diseases in rodents and monkeys and improve the health of overweight humans. Both IF and CR enhance cardiovascular and brain functions and improve several risk factors for coronary artery disease and stroke including a reduction in blood pressure and increased insulin sensitivity. Cardiovascular stress adaptation is improved and heart rate variability is increased in rodents maintained on an IF or a CR diet. Moreover, rodents maintained on an IF regimen exhibit increased resistance of heart and brain cells to ischemic injury in experimental models of myocardial infarction and stroke. The beneficial effects of IF and CR result from at least two mechanisms--reduced oxidative damage and increased cellular stress resistance. Recent findings suggest that some of the beneficial effects of IF on both the cardiovascular system and the brain are mediated by brain-derived neurotrophic factor signaling in the brain. Interestingly, cellular and molecular effects of IF and CR on the cardiovascular system and the brain are similar to those of regular physical exercise, suggesting shared mechanisms. A better understanding of the cellular and molecular mechanisms by which IF and CR affect the blood vessels and heart and brain cells will likely lead to novel preventative and therapeutic strategies for extending health span."

Beneficial effects of intermittent fasting and caloric restriction on the cardiovascular and cerebrovascular systems.
J Nutr Biochem. 2005 Mar;16(3):129-37.



6. "Although all cells in the body require energy to survive and function properly, excessive calorie intake over long time periods can compromise cell function and promote disorders such as cardiovascular disease, type-2 diabetes and cancers. Accordingly, dietary restriction (DR; either caloric restriction or intermittent fasting, with maintained vitamin and mineral intake) can extend lifespan and can increase disease resistance. Recent studies have shown that DR can have profound effects on brain function and vulnerability to injury and disease. DR can protect neurons against degeneration in animal models of Alzheimer's, Parkinson's and Huntington's diseases and stroke. Moreover, DR can stimulate the production of new neurons from stem cells (neurogenesis) and can enhance synaptic plasticity, which may increase the ability of the brain to resist aging and restore function following injury. Interestingly, increasing the time interval between meals can have beneficial effects on the brain and overall health of mice that are independent of cumulative calorie intake."

Meal size and frequency affect neuronal plasticity and vulnerability to disease: cellular and molecular mechanisms.
J Neurochem. 2003 Feb;84(3):417-31.



7. "Dietary restriction has been shown to have several health benefits including increased insulin sensitivity, stress resistance, reduced morbidity, and increased life span.

"intermittent fasting resulted in beneficial effects that met or exceeded those of caloric restriction including reduced serum glucose and insulin levels and increased resistance of neurons in the brain to excitotoxic stress. Intermittent fasting therefore has beneficial effects on glucose regulation and neuronal resistance to injury in these mice that are independent of caloric intake."

Intermittent fasting dissociates beneficial effects of dietary restriction on glucose metabolism and neuronal resistance to injury from calorie intake. Proc Natl Acad Sci U S A. 2003 May 13; 100(10): 6216–6220.


Tittel: Sv: 1 måltid om dagen.
Skrevet av: Beefcake18. august 2007, 16:32
Intressant artikel om ämnet:

"Dr. Art De Vany describes himself as a scientist/athlete. He's competed in Olympic weightlifting, motocross, and even played minor league baseball. At 6'1" and 208 pounds, today he carries only 8% body fat. Pretty admirable. De Vany barely had time to do this interview. He was headed off to Colorado to ride in the KTM Rocky Mountain Raid, an adventure motorcycling event.

Oh, did I mention Dr. De Vany is pushing 70 years old?"


http://www.t-nation.com/readTopic.do?id=709484 (http://www.t-nation.com/readTopic.do?id=709484)

- Han överskattar nog dock GH's (tillväxthormon) anabola effekt. För det första så är GH inte särskilt anabolt hos vuxna människor, bara fettförbrännande. Och protein och karbo efter träning ökar GH-frisättning, inte tvärtom som han hävdar.

Men han säger mycket annat intressant som går på IF, åldrande och hälsa. Han har ju också definitivt åldern och formen att backa upp det med.


Tittel: Sv: 1 måltid om dagen (periodisk fasta)
Skrevet av: Tox18. august 2007, 16:54
Lurer på en ting, Beefcake.

Jeg trener som regel på ganske tom mage, men jeg har en shake som jeg drikker under trening med ca. 30-35g Karbo og 20-25g protein, og en shake etter trening med ca 45-55g karbo og 35-50g proteiner.

Vis jeg drikker den shaken under trening, har det noen negative virkninger for Gh hormonene, stress for magen eller noe annet? Jeg synes det hjelper, siden jeg trener opptil 1,5 timer enkelte ganger.


Tittel: Sv: 1 måltid om dagen (periodisk fasta)
Skrevet av: Beefcake18. august 2007, 17:12
Lurer på en ting, Beefcake.

Jeg trener som regel på ganske tom mage, men jeg har en shake som jeg drikker under trening med ca. 30-35g Karbo og 20-25g protein, og en shake etter trening med ca 45-55g karbo og 35-50g proteiner.

Vis jeg drikker den shaken under trening, har det noen negative virkninger for Gh hormonene, stress for magen eller noe annet? Jeg synes det hjelper, siden jeg trener opptil 1,5 timer enkelte ganger.

Nej, absolut inte. Protein/karbo-intag i samband med träning ökar GH-frigöringen:

"Our laboratory reported that a protein and carbohydrate supplement consumed before and immediately after resistance exercise enhanced the acute GH response from 0 to 30 min postexercise compared with a noncaloric placebo despite similar glucose levels between trials. Compared with placebo, a protein and carbohydrate supplement consumed immediately and 120 min after resistance exercise increased GH during late recovery when glucose levels were lower. "

Influence of Nutrition on Responses to Resistance Training. Medicine and science in sports and exercise. 2004, vol. 36, no4, pp. 689-696



Dock är GH inte speciellt muskelbyggande för vuxna människor (men möjligtvis för äldre):

"In contrast, the currently available data suggest that GH administration alone or in combination with strength exercise has little, if any, effect on muscle volume, strength and fibre composition in non-GH-deficient healthy young individuals. This assumption is supported by the lack of evidence for a significant performance-enhancing effect of GH in athletes. However, further studies will be necessary to define patient populations which might benefit from GH treatment like frail elderly individuals in whom a GH-induced change into a more youthful muscle fibre composition has been reported."

Effects of growth hormone on skeletal muscle. Horm Res. 2002;58 Suppl 3:43-8.



Det är essentiella aminosyror, alltså protein, som är muskelbyggande. 


Tittel: Sv: 1 måltid om dagen (periodisk fasta)
Skrevet av: Tox18. august 2007, 17:22
Takk for svar, da fortsetter jeg med en shake under trening og en etter :)


Tittel: Sv: 1 måltid om dagen (periodisk fasta)
Skrevet av: Tox18. august 2007, 17:27
Fant denne artikkelen på pubmed:

Muscle is a target of growth hormone (GH) action and a major contributor to whole body metabolism. Little is known about how GH regulates metabolic processes in muscle or the extent to which muscle contributes to changes in whole body substrate metabolism during GH treatment. To identify GH-responsive genes that regulate substrate metabolism in muscle, we studied six hypopituitary men who underwent whole body metabolic measurement and skeletal muscle biopsies before and after 2 wk of GH treatment (0.5 mg/day). Transcript profiles of four subjects were analyzed using Affymetrix GeneChips. Serum insulin-like growth factor I (IGF-I) and procollagens I and III were measured by RIA. GH increased serum IGF-I and procollagens I and III, enhanced whole body lipid oxidation, reduced carbohydrate oxidation, and stimulated protein synthesis. It induced gene expression of IGF-I and collagens in muscle. GH reduced expression of several enzymes regulating lipid oxidation and energy production. It reduced calpain 3, increased ribosomal protein L38 expression, and displayed mixed effects on genes encoding myofibrillar proteins. It increased expression of circadian gene CLOCK, and reduced that of PERIOD. In summary, GH exerted concordant effects on muscle expression and blood levels of IGF-I and collagens. It induced changes in genes regulating protein metabolism in parallel with a whole body anabolic effect. The discordance between muscle gene expression profiles and metabolic responses suggests that muscle is unlikely to contribute to GH-induced stimulation of whole body energy and lipid metabolism. GH may regulate circadian function in skeletal muscle by modulating circadian gene expression with possible metabolic consequences.

1: Am J Physiol Endocrinol Metab. 2007 Jul;293(1):E364-71. Epub 2007 Apr 24.

Siden GH øker Proteinsyntesen så er det vel anabolt?


Tittel: Sv: 1 måltid om dagen (periodisk fasta)
Skrevet av: Beefcake18. august 2007, 17:36
Fant denne artikkelen på pubmed:

Muscle is a target of growth hormone (GH) action and a major contributor to whole body metabolism. Little is known about how GH regulates metabolic processes in muscle or the extent to which muscle contributes to changes in whole body substrate metabolism during GH treatment. To identify GH-responsive genes that regulate substrate metabolism in muscle, we studied six hypopituitary men who underwent whole body metabolic measurement and skeletal muscle biopsies before and after 2 wk of GH treatment (0.5 mg/day). Transcript profiles of four subjects were analyzed using Affymetrix GeneChips. Serum insulin-like growth factor I (IGF-I) and procollagens I and III were measured by RIA. GH increased serum IGF-I and procollagens I and III, enhanced whole body lipid oxidation, reduced carbohydrate oxidation, and stimulated protein synthesis. It induced gene expression of IGF-I and collagens in muscle. GH reduced expression of several enzymes regulating lipid oxidation and energy production. It reduced calpain 3, increased ribosomal protein L38 expression, and displayed mixed effects on genes encoding myofibrillar proteins. It increased expression of circadian gene CLOCK, and reduced that of PERIOD. In summary, GH exerted concordant effects on muscle expression and blood levels of IGF-I and collagens. It induced changes in genes regulating protein metabolism in parallel with a whole body anabolic effect. The discordance between muscle gene expression profiles and metabolic responses suggests that muscle is unlikely to contribute to GH-induced stimulation of whole body energy and lipid metabolism. GH may regulate circadian function in skeletal muscle by modulating circadian gene expression with possible metabolic consequences.

1: Am J Physiol Endocrinol Metab. 2007 Jul;293(1):E364-71. Epub 2007 Apr 24.

Siden GH øker Proteinsyntesen så er det vel anabolt?

Jag har väl inte sagt något annat...? Det jag sa var att GH inte är speciellt muskelbyggande, inte att det inte alls är det. Dock har proteinintag i samband med träning betydligt större "effekt".

Det du frågade om var om det var om shaken under träning hade några negativa verkningar för GH-utsöndring, och det har det inte.

För övrigt så omhandlar den där studien supplementering med GH ("GH treatment (0.5 mg/day)") för folk som har fel på hypofysen.


Tittel: Sv: 1 måltid om dagen (periodisk fasta)
Skrevet av: Avalon17. september 2007, 15:17
Hmm, FØR jeg begynte å tenke på kosthold, spiste jeg 1-2måltider om dagen. Aldri på formiddagen, og måltidene besto stort sett av kjøtt, egg, ost, tja... Proteiner og fett rett og slett. Noe karbohydrater fikk jeg jo i meg, men var kresen og spiste hverken brød, poteter, frokostblandinger, bakevarer eller lignende.

Så fikk jeg beskjed om at jeg måtte "gjøre noe" med kostholdet. Spise hver 3.time, mer karbohydrater, sky fett som pesten osv. Jeg la om vanene mine, og i tillegg til å legge på meg 6kilo, er jeg sulten HELE tiden. Kroppen higer etter noe hele tiden, og jeg har faktisk begynt å spise godteri og kaker! Før kunne jeg ikke drømme om å spise bakevarer, kroppen ville ikke ha det!

Så nå har jeg bestemt meg for å gå tilbake til de gamle vanene - som var det kroppen ville ha. Jeg gikk aldri sulten, og var i mitt livs form.


Friend of Avalon


Tittel: Sv: 1 måltid om dagen (periodisk fasta)
Skrevet av: Woody18. september 2007, 13:04
Ser at de som har prøvd dette har brukt "tilskudd" om dagen og spist et stort måltid om kvelden.
Med tilskudd menes proteinpulvet, etc? Vil det fungere på samme måte hvis man lever på proteinshaker om dagen, og spiser et stort måltid om kvelden? Da vil jo man slippe å spise et helt enormt måltid om kvelden vel?


Tittel: Sv: 1 måltid om dagen (periodisk fasta)
Skrevet av: Tynnj18. september 2007, 13:09
Ser at de som har prøvd dette har brukt "tilskudd" om dagen og spist et stort måltid om kvelden.
Med tilskudd menes proteinpulvet, etc? Vil det fungere på samme måte hvis man lever på proteinshaker om dagen, og spiser et stort måltid om kvelden? Da vil jo man slippe å spise et helt enormt måltid om kvelden vel?

Hvordan tror du tarmene ender opp hvis du kun drikker shakes daglig? ;)


Tittel: Sv: 1 måltid om dagen (periodisk fasta)
Skrevet av: Beefcake18. september 2007, 13:11
Ser at de som har prøvd dette har brukt "tilskudd" om dagen og spist et stort måltid om kvelden.
Med tilskudd menes proteinpulvet, etc? Vil det fungere på samme måte hvis man lever på proteinshaker om dagen, og spiser et stort måltid om kvelden? Da vil jo man slippe å spise et helt enormt måltid om kvelden vel?

Vilka syftar du på när du säger "de som har prøvd dette"?

Nej, det vill inte "funka" på samma sätt med proteinshaker på dagen. Då blir det inte längre att betrakta som fasta.

D :)


Tittel: Sv: 1 måltid om dagen (periodisk fasta)
Skrevet av: pc-kr23. januar 2008, 18:05
Hallo!
Jeg har lyst til å prøve dette. Jeg trener litt kondis nå og da, og helkropsprogram for styrke 2-3 ganger i uka. Har hørt at en skal ha karbohydrater så nært etter trening som mulig. Strider ikke dette matprogrammet med dette, slik at treningen mister effekt?
Takk for meg


Tittel: Sv: 1 måltid om dagen (periodisk fasta)
Skrevet av: Beefcake23. januar 2008, 18:16
Hallo!
Jeg har lyst til å prøve dette. Jeg trener litt kondis nå og da, og helkropsprogram for styrke 2-3 ganger i uka. Har hørt at en skal ha karbohydrater så nært etter trening som mulig. Strider ikke dette matprogrammet med dette, slik at treningen mister effekt?
Takk for meg

Hvilket matprogram mener du?

I den typen av periodisk faste som denne tråden i hovedsak omhandler så er en av grunntankene å spise hovedparten av karbohydratene for dagen etter trening...

Et mindre måltid en time eller to før trening, deretter 2-3 store måltider i løpet av de etterfølgende 4-6 timene. Kun vann, kaffe og te resten av døgnet.


Tittel: Sv: 1 måltid om dagen (periodisk fasta)
Skrevet av: Prodigy9228. juni 2008, 14:45
Periodisk faste virker helt genialt, men jeg lurer litt, fordi: Når du trener, er det ikke slik at musklen vil ha næring i et par dager, kanskje dagen etter trening, fra proteiner osv osv, er det slik at kroppen klarer å "lagre" proteinene slik at de kan bli brukt senere liksom? Litt knotete spørsmål jeg stiller, men lurer litt.


Tittel: Sv: 1 måltid om dagen (periodisk fasta)
Skrevet av: fryseboks28. juni 2008, 20:05
Hva med mesteparten av karbs til frokost(2 måltider om dagen, frokost og middag)? Havregryn eller brød er veldig mye greiere enn å begynne å tilbrede kjøtt osv. tildig på morgenen.

Og 1-2 måltider om dagen betyr forsatt en liten mengde mat bestående av karbs rett etter trening?
Hva med før trening?


Tittel: Sv: 1 måltid om dagen (periodisk fasta)
Skrevet av: UpAndComming28. juni 2008, 20:16
Periodisk faste virker helt genialt, men jeg lurer litt, fordi: Når du trener, er det ikke slik at musklen vil ha næring i et par dager, kanskje dagen etter trening, fra proteiner osv osv, er det slik at kroppen klarer å "lagre" proteinene slik at de kan bli brukt senere liksom? Litt knotete spørsmål jeg stiller, men lurer litt.

Skjønner hva du mener, og ja - kroppen har en "forsinkelseseffekt" dersom du "overspiser" protein over en kort tid. Kroppen er ikke så du ser du. :)


Tittel: Sv: 1 måltid om dagen (periodisk fasta)
Skrevet av: Prodigy9228. juni 2008, 20:35
Skjønner hva du mener, og ja - kroppen har en "forsinkelseseffekt" dersom du "overspiser" protein over en kort tid. Kroppen er ikke så du ser du. :)

Takker for svar:) Honnør! Da satser jeg på å få begynt med dette iløpet av noen uker, blir spennende å se hvordan det går!


Tittel: Sv: 1 måltid om dagen (periodisk fasta)
Skrevet av: Junkfood-mannen07. februar 2009, 17:47
Skjønner hva du mener, og ja - kroppen har en "forsinkelseseffekt" dersom du "overspiser" protein over en kort tid. Kroppen er ikke så du ser du. :)

Har du kilde på dette? Har prøvd å finne selv men greier ikke. I så fall skal du (eller den som gjør det) få honnør.


Tittel: Sv: 1 måltid om dagen (periodisk fasta)
Skrevet av: ubertass07. februar 2009, 18:15
Holdt på med periodisk faste i heile 2008, noko som funka knallbra. Blei vanligvis 4 måltider om dagen. 1 før trening og resten etter trening.
No praktiserer eg Health And Fitness Concept.


Tittel: Sv: 1 måltid om dagen (periodisk fasta)
Skrevet av: Symbiose08. februar 2009, 01:31
Tror jeg skal prøve periodisk faste en stund fra nå av. Gjorde noe liknende før og merket ikke noe særlig ubehag. Er dritt lei av å planlegge når på dagen jeg skal spise hele tiden, i tillegg blir sansene skjerpet når man er litt sulten, istedet for å være sløv og jævlig når man er mett.

Så.. 9.februar starter det!


Tittel: Sv: 1 måltid om dagen (periodisk fasta)
Skrevet av: UpAndComming08. februar 2009, 12:16
Har du kilde på dette? Har prøvd å finne selv men greier ikke. I så fall skal du (eller den som gjør det) få honnør.

Det finnes kilder på det her inne, men søkemotoren her er ikke imponerende. Skal se om jeg finner det.... :)


Tittel: Sv: 1 måltid om dagen (periodisk fasta)
Skrevet av: hallo08. juni 2009, 18:01
Søkte på " 1 måltid om dagen", da jeg har lyst å prøve dette, og fikk opp denne posten.

Det jeg lurer på er om noen kunne nevne et konkret eksempel på dette ene måltidet.

Det er vel også ekstremt viktig å drikke ekstra med vann mens man lever på denne måten?


Tittel: Sv: 1 måltid om dagen (periodisk fasta)
Skrevet av: Kengdal08. juni 2009, 18:53
Søkte på " 1 måltid om dagen", da jeg har lyst å prøve dette, og fikk opp denne posten.

Det jeg lurer på er om noen kunne nevne et konkret eksempel på dette ene måltidet.
F.eks:
500 gram karbonadedeig, grønnsaker/salat, salsa,100 gram ost og 3 pita brød.
Til dessert et beger med yogurt, en neve med mandler og et par opphakkede frukt.

Ca 2200 kcal, Protein: 160 gram, Karb: 230 gram, Fett: 75 gram


Det er vel også ekstremt viktig å drikke ekstra med vann mens man lever på denne måten?
Hvorfor skal det være det? Kroppen trenger verken mer, eller mindre vann avhengig av måltidfrekvensen. Forøvrig er det tull å drikke så mye vann som mange anbefaler.


Tittel: Sv: 1 måltid om dagen (periodisk fasta)
Skrevet av: Scarface08. juni 2009, 19:23
Er det egentlig noen profesjonelle idretsutøvere eller personer innen for fitness & bygging som kun spiser et måltid om dagen ?
Argumentasjonen for at det går like bra å spise et måltid høres jo fornuftig ut men er det mange som egentlig gjør det ?


Tittel: Sv: 1 måltid om dagen (periodisk fasta)
Skrevet av: hallo09. juni 2009, 14:23
ok skjønner...Men man må vel nesten spise et måltid før trening for å kunne yte maks.. har noen et eksempel på dette måltidet også? :P


Tittel: Sv: 1 måltid om dagen (periodisk fasta)
Skrevet av: Kengdal09. juni 2009, 15:53
ok skjønner...Men man må vel nesten spise et måltid før trening for å kunne yte maks.. har noen et eksempel på dette måltidet også? :P
Før trening spis 200-300 gram magert kjøtt, salat/grønnsaker og et par frukt.
Rett etter trening kan du gjerne legge inn litt raskere karbohydrater sammen med protein.



Tittel: Sv: 1 måltid om dagen (periodisk fasta)
Skrevet av: Sup09. juni 2009, 17:00
Noen som kan gi eksempler på store byggere som gjør det her eller? spiser få måltider bare? eller kommer dere bare med teorier og teorier etc..? greit det nevnes serge nubret her som et eksempel. Men fler? siden det skal være så jævlig effektivt liksom? serge var ikke så sinnsykt stor heller i følge http://www.schwarzenegger.it/mro/nubret.html (http://www.schwarzenegger.it/mro/nubret.html) var han: Off Season Weight: 100 kg, Competition Weight: 96 kg. Så når jeg tenker på store byggere tenker jeg hvertfall 100+ på scenen (marius grattrud typer inkludereres her så klart).


Tittel: Sv: 1 måltid om dagen (periodisk fasta)
Skrevet av: Kengdal09. juni 2009, 18:17
Noen som kan gi eksempler på store byggere som gjør det her eller? spiser få måltider bare? eller kommer dere bare med teorier og teorier etc..? greit det nevnes serge nubret her som et eksempel. Men fler? siden det skal være så jævlig effektivt liksom? serge var ikke så sinnsykt stor heller i følge http://www.schwarzenegger.it/mro/nubret.html (http://www.schwarzenegger.it/mro/nubret.html) var han: Off Season Weight: 100 kg, Competition Weight: 96 kg. Så når jeg tenker på store byggere tenker jeg hvertfall 100+ på scenen (marius grattrud typer inkludereres her så klart).

Hva som er ”jævlig” effektivt/optimalt for den vanlige mannen i gata som ønsker en bedre form, og hva som er optimalt for en proff bygger som setter 1-2g testo i uka, x-antall enheter med HGH og Insulin er to vidt forskjellige ting. Og dette blir bare tull å sammenligne, så ikke vist å dra det noe lenger. (Nå sier ikke jeg at Marius Gratterud benytter seg noe av dette!)


Periodisk faste har masse forskning bak seg, og har vist seg meget effektivt i flere sammenhenger.
Sjekk ut Martin Berkhan sin side http://leangains.com/ (http://leangains.com/) og boken Eat Stop Eat http://eatstopeat.com/ (http://eatstopeat.com/) av Brad Pilon, for mer informasjon.


Legger også ved en veldig bra objektiv artikkel av Alan Argon for de som vil sette seg dypere inn i dette temaet. Tipper dette skal svare på de fleste spm rundt temaet.  :)

http://www.alanaragon.com/an-objective-look-at-intermittent-fasting.html (http://www.alanaragon.com/an-objective-look-at-intermittent-fasting.html)
Sitat
An Objective Look at Intermittent Fasting
By Alan Aragon & Ryan Zielonka
 
Copyright © By Alan Aragon
August 8th, 2007
_____________________________________________________________________________________
 
Introduction
 
Over time, the ancient practice of fasting seems to periodically find its way into modern fitness subcultures. Despite its purported physiological and psychological benefits, scientific data is far from unanimously supporting it. Are there any physiological advantages to increasing or decreasing meal frequency? What are the downsides to intermittent fasting? What are the health advantages shared by fasting, exercise, and caloric restriction? Are there detrimental effects of resistance training in a fasted state? Anecdotal data is fraught with suggestion-driven bias, so this paper will focus on what's been demonstrated objectively in scientific research.
 
Meal Frequency - Hot Dogma & Cold Facts
 
Since the infancy of  health-nut culture, it's been decreed that one must eat every 2-3 hours, thus minimizing muscle breakdown while keeping the metabolic engine revving. Tupperware and coolers in gyms and cars were (and still are) a common sight, perceived by the public as a sign of diligence and discipline. Alas, the long-held belief in a higher-is-better frequency has been examined with the lens of science, and some interesting data has surfaced.
 
Effects on Health & Thermogenesis
 
Research indicates that a haphazard meal frequency, not necessarily a lower frequency, negatively impacts thermogenesis, blood lipids, and insulin sensitivity [1,2]. Contrary to popular belief, a high frequency has no thermodynamic advantage over a low frequency under calorie-controlled conditions (as opposed to ad libitium or free-living conditions) using 24-hr indirect calorimetry [3,4]. So much for the magic of stoking the metabolic furnace with an extreme grazing pattern. It bears mentioning that lower 24-hour insulin levels as well as lower fasting and total LDL-cholesterol levels have been observed with higher meal frequencies [5,6]. However, in discovering this, studies have used unrealistic protocols for the higher frequency treatments, comparing 3 meals to 9 or 17 meals per day.
 
Effects on Body Composition
 
With little exception [7,8], the majority of controlled intervention trials show no improvement in body composition with a higher meal frequency, with treatments ranging from 1 to 9 meals per day [9-11,15]. Unfortunately, a scarcity of research examining meal frequency's effect on body composition under conditions of exercise exists in the literature. To further confound the data, results from studies are mixed. The singular full-length published controlled trial showing a body composition benefit of higher meal frequency (6 versus 3) is limited by its poor study design. In the trial, boxers consumed a 1200 kcal liquid diet over a 2 week period [8]. The 6-a-day group retained more lean mass than the 3-a-day group.
 
In contrast to the boxer study, a recent abstract presented at the 12th Annual Congress of the European College of Sport Science reported the superiority of 3 meals a day to 6 meals a day for gaining lean mass during a 12 week period involving strength training [12]. Too bad the 3-a-day group also experienced a trend towards fat gain. This raises the possibility that the 3-a-day group simply ate more calories overall. This wouldn't be surprising, considering that comparative research shows an association of greater hunger with meal frequency reduction.
 
Effects on Appetite
 
Studies indicating the disappearance or lack of hunger in dieters occurs in either complete starvation, or very low calorie regimes (800 kcal/day or less) [13,14]. Much of this data is irrelevant for most of you reading this. Furthermore, none of those studies systematically measured appetite throughout waking hours. Convenience issues aside, for the purposes of controlling appetite, research indicates the superiority of a higher frequency over a lower one.
 
In two separate studies led by Speechly, both lean and obese subjects had greater appetite control when pre-test meals were consumed at frequent intervals, in contrast to the same amount of food consumed at a single meal [15,16]. In the ad libitium test meal that followed the pre-test meals, subjects given the single meal consumed on average 26.5% more calories.
 
Stote's team compared 1 versus 3 meals per day [17]. Among other results, the 1-a-day group reported significantly higher levels of  hunger and an increased desire to eat, with the severity of both phenomena increasing throughout the length of the trial. In a recent alternate-day fasting study [18], Heilbronn’s team concluded, “Overall, these results suggest that a prolonged schedule of fasting and feasting would be marred by aversive subjective states (eg, hunger and irritability), which would likely limit the ability of most individuals to sustain this eating pattern.”
 
In a recent review, Johnstone suggests that a hierarchy of hunger response exists (at least in obese subjects), whereby hunger directly correlates with the severity of the caloric deficit, citing fasting as the obvious limit of acute deficit [13]. The persistence of hunger was one of the primary reasons he did not recommend fasting as the optimal dieting strategy, despite having been a principal investigator in fasting research. To quote the paper’s conclusion, “There is, however, the problem of elevated hunger during food restriction and this may provide too great a challenge to a ‘faster’ in not breaking compliance to the dieting regime and reaching for the biscuit barrel.”
 
Skipping Breakfast = Not Too Brilliant
 
Rampersaud's team examined the results of 47 studies on various effects of breakfast consumption among children and adolescents [19]. Interestingly, while breakfast eaters consumed more daily calories, they were less likely to be overweight. Children who consistently ate breakfast tended to have superior nutritional profiles. This concurs with a cohesive body of data indicating that adults who eat breakfast meet their daily micronutrient needs better than habitual breakfast-skippers [20-22]. While cognitive effects are inconsistent in well-nourished children, breakfast skipping degrades mental performance in malnourished children. Overall, the evidence points to regular breakfast consumption improving cognitive function, test grades, school attendance, memory, and nutrient status. The latter effect pertains to macronutrients and essential vitamins and minerals. The impact of skipping breakfast on the intake of other functional nutrients hasn't been studied.
 
In a controlled intervention trial on lean subjects, Farshchi's team found that skipping breakfast decreased post-meal insulin sensitivity and increased LDL-cholesterol, despite a high (6-a-day) meal frequency [23]. This data points to the possibility that the body is "metabolically primed" to eat a meal soon after an overnight fast.
 
Concurring with the above results, noted protein researcher Donald Layman asserted in a recent review that the most critical meal of the day is breakfast after an overnight fast [24]. This is partially due to circadian protein synthesis rates being lowest at this time. He states that the anabolic impact of a meal lasts roughly 5-6 hours based on the rate of post-meal amino acid metabolism, therefore, dietary protein should be provided at approximately 5-hr intervals throughout the day. This recommendation can be challenged by the fact that other studies show longer durations of plasma glucose and amino acid elevations caused by casein or a mixed meal [25,26]. However, the latter research didn't measure the effect of exercise on plasma amino acid flux. In the final analysis, Layman's suggestions are a safe bet without any major convenience impingements.
 
In three separate controlled experiments, Benton and Parker examined the effect of breakfast versus fasting on cognition [27]. In the first study, fasted subjects took significantly more time than the fed group to complete both the spatial memory task and the word recall. In the second study measuring information processing and short-term memory decay, the fasted group lacked the improvements shown in the breakfast group. In the final trial, memory and intelligence were measured. Although breakfast didn't enhance abstract thought, it was superior to fasting for recalling a story read aloud. The researchers concluded that these trials were in agreement with a substantial body of previous research demonstrating that breakfast benefits memory.
 
On the observational research front, the National Weight Control Registry (NWCR) is the largest ongoing study of individuals who have successfully maintained substantial weight loss over the long term. To qualify, participants must maintain a weight loss of at least 13.6 kg (30 lb) for at least one year. According to a formal analysis led by Wyatt [28], 2313 subjects (78%) eat breakfast every day. Only 114 subjects (4%) reported skipping breakfast. This obviously isn’t cause-and-effect data, but it shows the crucial commonalities in the habits of dieters with long-term success. Daily breakfast is clearly one of those habits.
 
Intermittent Fasting Human Research – Interesting But Inconclusive
 
Alternate-Day Fasting
 
Intermittent fasting (IF) can be any number of variations of feed/fast intervals. Alternate-day fasting (ADF) is simply defined by its name. As of this writing, the literature on ADF contains 3 human trials conducted within the last 2 years [18,29,30]. Control groups were absent in all of those studies. As such, no comparative conclusions can be drawn between ADF and linear caloric intake. Animal research has shown promise for the health effects of ADF.  However, human research hasn’t quite lived up to the luck of rats. Nevertheless, the data still provides food for thought and further investigation.
 
Heilbronn's team put non-obese men and women on an ADF for a total of 22 days [29]. Subjects lost an average of 2.1 kg total bodyweight despite instructions to eat double their typical day’s intake every other day. Men maintained normal glucose metabolism and improved insulin response. Impaired glucose tolerance occurred in women by the end of the trial. Although a trend toward increases in resistance to stress occurred in the study, both men and women showed no changes in gene expression involved with fatty acid oxidation.
 
In another 22-day ADF study led by Heilbronn, non-obese subjects lost an average of 2.5% of
initial bodyweight [18]. Beneficial effects of ADF included a decrease in fasting insulin levels and respiratory quotient, indicating an average fat oxidation increase of roughly 15g per day. Unfortunately, there was an increase in hunger on the first fasting day, a condition that remained elevated for the duration of the trial.
 
Halberg's team examined the effect of an ADF for a total of 14 days on non-obese young men [30], and observed an increase in insulin sensitivity. In contrast to the previously discussed study, no change in bodyweight or bodyfat occurred. As a result of the ADF, insulin sensitivity and glucose uptake in muscle increased. However, there was also an increased sensitivity, or uptake-readiness in the fat cells, evidenced by an inhibition of insulin-mediated adipose tissue lipolysis. The next study we'll examine deserves its own section, but not for the reasons you might expect.
 
A "Controlled" Study?
 
A recent study led by Stote compared the effects of 1 meal with 3 meals per day, and was the first trial of its kind to control calories between randomly assigned groups [17]. Curiously, the 1-a-day group lost slightly more bodyweight and bodyfat, and gained a small amount of lean mass. Given those results, it's heralded in some fitness circles as the long-awaited shred of research supporting Ramadan-style (12-16 hour daily) fasting for achieving the Holy Grail of body re-composition.
 
As always, things are never as simple as they seem once the details are exposed. A number of serious design flaws, including common ones such as a small sample size (15 participants completed the trial) and short duration (2 week lead-in, 6 week treatment periods) plague the quality of the conclusions. The withdrawal of 5 subjects was a 28% dropout rate, which raises the huge question of how different the results might have been if the participants hung in there. The authors noted this was anomalously high compared to the typical dropout rate from feeding studies at their facility, which is roughly 6-7%. Statistical outcomes can easily swing either direction due to individual differences in a small sample. Now let’s take a look at how the key limitation of this trial cripples its validity.
 
The most crucial short-sight of the investigation was its use of bioelectrical impedance analysis (BIA) for body composition assessment. In a previous study illustrating its inaccuracy for fasting protocols, Faintuch’s team used BIA to measure body composition changes in non-obese subjects undergoing a 42 day fast, consuming only water, vitamins, and electrolytes [31]. BIA registered an unrealistic 32% decrease in bodyfat, and an overall gain in lean mass. The researchers themselves concluded that these impossible readings proved BIA an inappropriate method for this type of protocol. It’s baffling that Stote chose BIA out of all the available methods, given BIA’s woeful track record in fasting research, likely attributable to the aggressive water redistribution found in fasting patients. Since we don't have reliable readings of the study's critical endpoints, its results are basically worthless.
 
Enter Ramadan - Keep Your Eyes On The Road
 
Ramadan is considered by practicing Muslims to be the most important period of religious observation in the Islamic calendar. In its strictest version, a complete food and fluid fast is undergone from sunrise to sunset (12-16 hours). This routine is carried out daily for a month. Unsurprisingly, traffic accidents peak during this time, alongside a reduction in working hours [32]. Traffic injuries are the second major cause of death in the United Arab Emirates, with the bulk of the accidents occurring between 8am and 2pm [33]. Research consistently shows a decrease in daytime alertness, mood, and wakefulness during the fasting month of Ramadan [32-35]. Physical performance - speed, agility, and endurance declined in professional soccer players observing Ramadan [36]. Their performance remained low for two weeks post-Ramadan.
 
Fasting & Exercise - Common Effects
 
On the Heels of Caloric Restriction
 
Caloric restriction (CR), defined as a sustained linear calorie reduction without malnutrition, has a substantive body of animal data supporting its benefits on a number of clinical endpoints. Human data is steadily emerging to validate it. [35-37]. Whether or not IF is as effective as CR in humans will be determined by further research, but it appears effective at least in improving HDL levels in women, and insulin sensitivity across the board. Whether IF continues to show detrimental effects on glucose tolerance in women remains to be seen. Improvements in insulin sensitivity, glucose tolerance (in men at least), bodyweight/bodyfat, blood pressure, blood lipids, and heart rate are commonly cited benefits of IF & CR. The question is, can exercise achieve the aforementioned cardiovascular/metabolic benefits without the inherent downsides of periodic food deprivation? The scientifically valid answer is yes [40,41].
 
Neuroprotective Benefits
 
One of the highlighted benefits of IF & CR is the ability to prevent aging symptoms of the brain and nervous system. Brain-derived neurotrophic factor (BDNF) is one of a family of brain-based proteins responsible for the survival and growth of neurons involved with memory and learning. Preventing a decline in BDNF can thus prevent and/or lessen the progression of  neurodegenerative disorders. IF and CR have both been found to increase BDNF activity [42]. However, few are aware of the fact that exercise has also been demonstrated to elevate BDNF [43], and the degree of effect appears to be intensity-dependent [44]. In a recent example of this phenomenon, Winter's team found that in comparison to low impact aerobic running and a period of rest, vocabulary learning was 20% faster after high impact anaerobic sprints [45]. Ironically, although fasting can have preventive effects on neurodegeneration, its track record in improving human cognition is bleak.
 
With all this great data on the common neuro-protective and cardio-protective benefits shared by fasting and exercise, why not combine the two and train in a fasted state? Fasted cardio-respiratory training research has been covered elsewhere [46]. The next section will discuss the effects of fasted resistance training.
 
Fasted Resistance Training = Not Optimal
 
Regardless of the inconsistency of performance data on fed versus fasted subjects, the combination of fasting and resistance training has never been a good idea from the standpoint of optimizing protein synthesis and inhibiting protein breakdown.
 
Recent research by Baty's team showed no resistance training performance benefit of a protein-carb solution taken pre, during, and postworkout [47]. However, two indicators of muscle damage were elevated in the fasted training placebo group. Their myoglobin levels approached significance halfway through the exercise bout, and were significantly elevated 6 hours postexercise. Creatine kinase levels were also significantly elevated 24 hours postexercise.
 
Tipton's team compared the effect of an immediate pre-resistance training dose of essential amino acids + carbohydrate (EAA+CHO) with the same treatment immediately postworkout [48]. 262% more amino acid uptake was seen in the pre-group compared to the post-group. In a subsequent study, Tipton used a similar protocol with 20g whey protein only, administered either immediately pre- or immediately postworkout [49]. Although no significant differences in protein synthesis were seen, Tipton noted that the study was underpowered to detect differences in such a small sample size. He suggested that a protein-synthetic increase would be seen in the preworkout treatment if there were approximately double the number of subjects. Also of note is that 4 of the 8 subjects in the pre-group had greater amino acid uptake than any of the subjects in post-group. Furthermore, it’s highly likely that more protein synthesis would be seen in the pre-group if carbohydrate was taken with the protein, as was the case in Tipton’s previous study.
 
Bird's team saw muscle-preserving effects of an EAA+CHO solution ingested during training after a 4-hour fast [50]. The EAA+CHO treatment suppressed any cortisol increase, whereas the fasted group's cortisol levels rose 105% by the end of the training bout. 3-methylhistidine (3MH – an indicator of myofibrillar protein degredation) levels in the fasted group were elevated by 56% 2 days after the exercise bout, whereas 3MH levels the EAA+CHO group were reduced by 27%. Apparently, even a partial fast before resistance training can negatively impact muscle protein status.
 
Research Summary
 
Meal Frequency
 
§        A haphazard/randomly variable meal frequency, not necessarily a lower frequency, negatively impacts thermogenesis, blood lipids, and insulin sensitivity.
§        Within a day, a higher frequency has no thermodynamic advantage over a lower frequency under controlled conditions.
§        The majority of controlled intervention trials show no improvement in body composition with a higher meal frequency.
§        Studies indicating the disappearance or lack of hunger in dieters occur in either complete starvation, or very low calorie VLCD regimes (800 kcal/day or less).
§        Hunger is a persistent problem with reduced meal frequency in non-starvation and other protocols with calories above VLCD levels.
§        For controlling appetite, the majority of  research indicates the superiority of a higher meal frequency.
§        The body appears to be "metabolically primed" to receive calories and nutrients after an overnight fast. Breakfast is a particularly beneficial time to have dietary protein, since muscle protein synthethis rates are typically lowest at this time.
§       Overall, both experimental and observational research points to breakfast improving memory, test grades, school attendance, nutrient status, weight control, and muscle protein synthesis.
 
Intermittent Fasting
 
§        Animal research has shown a number of positive health effects of ADF and CR.
§        Human ADF research is scarce and less consistent than animal research, showing both benefits (insulin sensitivity is the most consistent outcome) and risks (impaired glucose tolerance in women).
§        So far, control groups are absent in all human ADF studies. Thus, no comparative conclusions can be drawn between ADF and linear caloric intake.
§        The validity of the single published controlled trial to date (Stote, et al) comparing 1 versus 3 meals is heavily confounded by an exceptionally high dropout rate in the 1-a-day group, and the use of BIA to measure body composition.
§        The 1-a-day group reported increasing hunger levels throughout the length of the trial, echoing the problem of hunger with a reduced meal frequency seen in other similar research.
§        Ramadan fasting (12-16 hours per day, sunrise to sunset) decreases daytime alertness, mood, wakefulness, competitive athletic performance, and  increases the incidence of traffic accidents. It's difficult to determine the relative contributions of dehydration and a lack of food to these adverse phenomena.
§        The effects of exercise and meal frequency on body composition is an interesting but largely unexplored area of research.
 
Fasting & Exercise
 
§        Improvements in insulin sensitivity, glucose tolerance (except in women undergoing ADF), bodyweight/bodyfat, blood pressure, blood lipids, and heart rate are commonly cited benefits of IF & CR. 
§        All of the above benefits can be achieved by exercise, minus the downsides of fasting.
§        IF and CR have both been found to have neuroprotective effects by increasing BDNF levels.
§        A growing body of research shows that exercise can also increase BDNF, and the degree of effect appears to be intensity-dependent.
§        Based on the limited available data, resistance training performance, especially if its not particularly voluminous, might not be enhanced by preworkout EAA+CHO.
§        Despite equivocal performance effects of pre- or midworkout EAA+CHO, it minimizes muscle damage that occurs from fasted resistance training.
§        Immediate preworkout protein and/or EAA+CHO increases protein synthesis more than fasted resistance training with those substrates ingested immediately postworkout.
§        It’s possible that a partial fast (as short as 4 hours) before resistance training can negatively impact muscle protein status.
 
Conclusion
 
It's given that personal goals and individual response are the ultimate navigators of any protocol.  Therefore, training and meal schedules should be built upon individual preferences & tolerances, which undoubtedly will differ. However, the purpose of this article is to arm the reader with the facts, so that opinions and anecdotes can be judged accordingly. Personal testimony is invariably biased by the powerful placebo effect of suggestion, and sometimes by ulterior agenda. Science is perched on one end of the epistemological spectrum, and hearsay is on the opposite end. As the evidence clearly indicates, IF is not a bed of roses minus the thorns - there are definite pros and cons.
 
In the world of fitness, recommendations for improving performance and body composition often gain blind acceptance despite a dearth of objective data. This is common in a field where high hopes and obsessive-compulsive tendencies are united with false appeals and incomplete information. In order to be proven effective beyond the mere power of suggestion, supposed truths must be put through the crucible of science. Drawing conclusions from baseless assumptions is a good way to get nowhere - fast.
 
References
 
Farshchi HR, et al. Beneficial metabolic effects of regular meal frequency on dietary thermogenesis, insulin sensitivity, and fasting lipid profiles in healthy obese women. Am J Clin Nutr. 2005 Jan;81(1):16-24.
Farshchi HR, et al. Decreased thermic effect of food after an irregular compared with a   regular meal pattern in healthy lean women. Int J Obes Relat Metab Disord. 2004 May;28(5):653-60.
Taylor MA, Garrow JS. Compared with nibbling, neither gorging nor a morning fast affect short-term energy balance in obese patients in a chamber calorimeter. Int J Obes Relat Metab Disord. 2001 Apr;25(4):519-28.
Verboeket-van de Venne WP, Westerterp KR. Influence of the feeding frequency on nutrient utilization in man: consequences for energy metabolism. Eur J Clin Nutr. 1991 Mar;45(3):161-9.
Rashidi MR. Effects of nibbling and gorging on lipid profiles, blood glucose and insulin levels in healthy subjects.
Saudi Med J. 2003 Sep;24(9):945-8.
Jenkins DJ. Nibbling versus gorging: metabolic advantages of increased meal frequency. N Engl J Med. 1989 Oct 5;321(14):929-34.
Swindells YE,  The metabolic response of young women to changes in the frequency of meals.  Br J Nutr. 1968 Dec;22(4):667-80.
Iwao S, et al.  Effects of meal frequency on body composition during weight control in boxers.  Scand J Med Sci Sports. 1996 Oct;6(5):265-72.
Young CM, Frequency of feeding, weight reduction, and body composition.  J Am Diet Assoc. 1971 Nov;59(5):466-72.
Antoine JM, et al.  Feeding frequency and nitrogen balance in weight-reducing obese women. Hum Nutr Clin Nutr. 1984 Jan;38(1):31-8.
Verboeket-van de Venne WP, et al. Frequency of feeding, weight reduction and energy metabolism. Int J Obese Relat Metab Disord. 1993 Jan;17(1):31-6.
Øyvind H, et al. The effect of meal frequency on body composition during 12 weeks of strength training (Abstract). 12th Annual Congress of the European College of Sport Science, 2007.
Johnstone AM. Fasting - the ultimate diet? Obes Rev. 2007 May;8(3):211-22.
Wadden, et al. Less food, less hunger: reports of appetite and symptoms in a controlled study of a protein-sparing modified fast. Int J Obes. 1987;11(3):239-49.
Speechly DP, Buffenstein R. Greater appetite control associated with an increased frequency of eating in lean males. Appetite. 1999 Dec;33(3):285-97.
Speechly DP, et al. Acute appetite reduction associated with an increased frequency of eating in obese males. Int J Obes Relat Metab Disord. 1999 Nov;23(11):1151-9.
Stote, et al. A controlled trial of reduced meal frequency without caloric restriction in healthy, normal-weight, middle-aged adults. Am J Clin Nutr. 2007 Apr;85(4):981-8.
Heilbronn, et al. Alternate-day fasting in nonobese subjects: effects on body weight, body composition, and energy metabolism. Am J Clin Nutr.
Rampersaud GC, et al. Breakfast habits, nutritional status, body weight, and academic performance in children and adolescents. J Am Diet Assoc. 2005 May;105(5):743-60; quiz 761-2.
Nicklas, et al. Impact of breakfast consumption on nutritional adequacy of the diets of young adults in Bogalusa, Louisiana: ethnic and gender contrasts. J Am Diet Assoc. 1998 Dec;98(12):1432-8.
Ruxton CH. Breakfast: a review of associations with measures of dietary intake, physiology and biochemistry. British J Nutr. 1997 Aug;78(2):199-213.
Morgan KJ.  The role of breakfast in the diet adequacy of the US population. J Am Coll Nutr. 1986 5(6):551-63.
Farshchi HR, et al. Deleterious effects of omitting breakfast on insulin sensitivity and fasting lipid profiles in healthy lean women. Am J Clin Nutr. 2005 Feb;81(2):388-96.
Layman DK. Protein quantity and quality at levels above the RDA improves adult weight loss. J Am Coll Nutr. 2004 Dec;23(6 Suppl):631S-636S.
Biorie Y, et al. Slow and fast dietary proteins differently modulate postprandial protein accretion. Proc Natl Acad Sci U S A. 1997 Dec 23;94(26):14930-5.
Capaldo B, et al. Splanchnic and leg substrate exchange after ingestion of a natural mixed meal in humans. Diabetes. 1999 May;48(5):958-66.
Benton D, Pearl Y. Breakfast, blood glucose, and cognition. Am J Clin Nutr. 1998 Apr;67(4):772S-778S.
Wyatt HR, et al. Long-term weight loss and breakfast in subjects in the National Weight Control Registry. 2002 Feb;10(2):78-82.
Heilbronn, et al. Glucose Tolerance and Skeletal Muscle Gene Expression in Response to Alternate Day Fasting. Obes Res. 2005 Mar;13(3):574-81.
Halberg, et al. Effect of intermittent fasting and refeeding on insulin action in healthy men. J Appl Phsiol. 2005 Dec;99(6):2128-36. Epub 2005 Jul 28.
Faintuch J, et al. Changes in body fluid and energy compartments during prolonged hunger strike. Rev Hosp Clin Fac Med Sao Paulo. 2000 Mar-Apr;55(2):47-54.
Roki R, et al. Physiological and chronobiological changes during Ramadan intermittent fasting. Ann Nutr Metab. 2004;48(4):296-303. Epub 2004 Sep 24.
Bener A, et al. Road traffic injuries in Al-Ain City, United Arab Emirates. J R Soc Health. 1992 Dec;112(6):273-6.
Roki R, et al. Daytime alertness, mood, psychomotor performances, and oral temperature during Ramadan intermittent fasting. Ann Nutr Metab. 2000;44(3):101-7.
Roky R, et al. Daytime sleepiness during Ramadan intermittent fasting: polysomnographic and quantitative waking EEG study. J Sleep Res. 2003 Jun;12(2):95-101.
Zerguini Y, et al. Impact of Ramadan on physical performance in professional soccer players. Br J Sports Med. 2007 Jun;41(6):398-400.
Fontana L, et al. Long-term calorie restriction is highly effective in reducing the risk for atherosclerosis in humans. Proc Natl Acad Sci U S A. 2004 Apr 27;101(17):6659-63.
Varady KA, Hellerstein MK. Alternate-day fasting and chronic disease prevention: a review of human and animal trials. Am J Clin Nutr. 2007 Jul;86(1):7-13.
Walfred RL, et al. The calorically restricted low-fat nutrient-dense diet in Biosphere 2 significantly lowers blood glucose, total leukocyte count, cholesterol, and blood pressure in humans. Proc Natl Acad Sci U S A. 1992 Dec 1;89(23):11533-7.
Lakka TA, Laaksonen DE. Physical activity in prevention and treatment of the metabolic syndrome. Appl Physiol Nutr Metab. 2007 Feb;32(1):76-88.
Carrol S, Dudfeld M. What is the relationship between exercise and metabolic abnormalities? A review of the metabolic syndrome. Sports Med. 2004;34(6):371-418.
Mattson MP, Wan R. Beneficial effects of intermittent fasting and caloric restriction on the cardiovascular and cerebrovascular systems. J Nutr Biochem. 2005 Mar;16(3):129-37.
Mattson MP. Neuroprotective signaling and the aging brain: take away my food and let me run. Brain Res. 2000 Dec 15;886(1-2):47-53.
Ferris LT, et al. The effect of acute exercise on serum brain-derived neurotrophic factor levels and cognitive function. Med Sci Sports Exerc. 2007 Apr;39(4):728-34.
Winter B. High impact running improves learning. Neurobiol Learn Mem. 2007 May;87(4):597-609.
Aragon A. Myths under the microscope. 2006. http://alanaragon.com/myths-under-the-microscope-the-fat-burning-zone-fasted-cardio.html (http://alanaragon.com/myths-under-the-microscope-the-fat-burning-zone-fasted-cardio.html)
Baty JJ, et al. The effect of a carbohydrate and protein supplement on resistance exercise performance, hormonal response, and muscle damage. J Strength Cond Res. 2007 May;21(2):321-9.
Tipton KD, et al. Timing of amino acid-carbohydrate ingestion alters anabolic response of muscle to resistance exercise. Am J Physiol Endocrinol Metab. 2001 Aug;281(2):E197-206.
Tipton KD, et al. Stimulation of net muscle protein synthesis by whey protein ingestion before and after exercise. Am J Physiol Endocrinol Metab. 2007 Jan;292(1):E71-6. Epub 2006 Aug 8.
Bird SP, et al. Liquid carbohydrate/essential amino acid ingestion during a short-term bout of resistance exercise suppresses myofibrillar protein degradation. Metabolism. 2006 May;55(5):570-7.



Tittel: Sv: 1 måltid om dagen (periodisk fasta)
Skrevet av: boberg09. juni 2009, 19:00
F.eks:
500 gram karbonadedeig, grønnsaker/salat, salsa,100 gram ost og 3 pita brød.
Til dessert et beger med yogurt, en neve med mandler og et par opphakkede frukt.

Ca 2200 kcal, Protein: 160 gram, Karb: 230 gram, Fett: 75 gram

Hmm, med karbonadedeigen, osten, yogurten og mandlene kommer jeg til 1200kkalorier, utgjør pitabrødene 1000kkalorier alene? :O


Tittel: Sv: 1 måltid om dagen (periodisk fasta)
Skrevet av: Kengdal09. juni 2009, 19:15
Hmm, med karbonadedeigen, osten, yogurten og mandlene kommer jeg til 1200kkalorier, utgjør pitabrødene 1000kkalorier alene? :O
Vet ikke hva du bruker, men jeg benytter meg av FitDay og dette er ganske nøyaktig. Så du må nok bare ta mitt ord på det. Gidder ikke skrive opp innholdet i hver enkelt matvare. Dette var bare et eksempel.


Tittel: Sv: 1 måltid om dagen (periodisk fasta)
Skrevet av: hallo10. juni 2009, 14:27
Hva er det som gjør at man mister mer fett viss man venter med å spise i 16 timer, for så og spise mye i 1 måltid?


Tittel: Sv: 1 måltid om dagen (periodisk fasta)
Skrevet av: webah23. juli 2009, 17:33
Går det ikke ann og gjøre en mellom ting, f.eks 2 måltider om dagen ?