Et interessant spørsmål, og et spørsmål som lett kan knyttes til flere spørsmål hva gjelder CNS og det endokrine systemet og deres betydning på cellenivå. For moro skyld poster jeg de siste studiene jeg fant på DOMS, siden det faktisk forskes endel på dette-
Du er nødt til å spise ja;Eur J Nutr. 2004 Jun;43(3):148-59. Epub 2004 Jan 06. Related Articles, Links
Further glycogen decrease during early recovery after eccentric exercise despite a high carbohydrate intake.
Zehnder M, Muelli M, Buchli R, Kuehne G, Boutellier U.
Exercise Physiology, Institute for Human Movement Sciences, Swiss Federal Institute of Technology and Institute of Physiology, University of Zurich, Zurich, Switzerland.
zehnderm@access.unizh.chBACKGROUND: Delayed onset muscle soreness (DOMS) is a well-known phenomenon of athletes. It has been reported from muscle biopsies that the rate of muscle glycogen resynthesis is reduced after eccentric compared to concentric exercise. AIM OF THE STUDY: Try to compensate by a carbohydrate (CHO)-rich diet the decelerated glycogen resynthesis after eccentric exercise, measured by magnetic resonance spectroscopy. METHODS: Glycogen, phosphocreatine, ATP, and Pi were measured in the human calf muscle. Twenty athletes divided into two groups (DOMS and CONTROL), reduced glycogen in M. gastrocnemius during two different running protocols. Additionally, 12 DOMS subjects performed an eccentric exercise while the CONTROL group rested. Subsequently, subjects consumed a CHO-rich diet (> 10 g/kg body mass/24 h). RESULTS: In both groups, glycogen has been reduced by about 50%. The first 2 h after exercise, glycogen dropped further (-15.6 +/- 15.7 mmol/ kg ww) in the DOMS but rose by +18.4 +/- 20.8 mmol/kg ww in the CONTROL group (P < 0.001). CONTROL subjects reached resting glycogen within 24 h (137 +/- 47 mmol/kg ww), while DOMS subjects needed more than one day (91 +/- 23 mmol/kg ww; P < 0.001). Pi and Pi/PCr, indicators of muscle injury, rose significantly in the DOMS but not in the CONTROL group. CONCLUSION: The diet rich in CHO's was not able to refill glycogen stores after eccentric exercise. Glycogen decreased even further during the beginning of recovery. This loss, which to our knowledge has not been measured before is probably the consequence of muscle cell damage and their reparation.
Publication Types:
Clinical Trial
Randomized Controlled Trial
PMID: 15168037 [PubMed - indexed for MEDLINE]
Yoga er bra? Venter spent på om det blir påvist at stretching har samme effekt:
J Strength Cond Res. 2004 Nov;18(4):723-9. Related Articles, Links
The effects of yoga training and a single bout of yoga on delayed onset muscle soreness in the lower extremity.
Boyle CA, Sayers SP, Jensen BE, Headley SA, Manos TM.
Department of Exercise Science and Sports Studies, Springfield College Allied Health Sciences Complex, Springfield, MA 01109, USA.
The purpose of this study was to determine the effects of yoga training and a single bout of yoga on the intensity of delayed onset muscle soreness (DOMS). 24 yoga-trained (YT; n = 12) and non-yoga-trained (CON; n = 12), matched women volunteers were administered a DOMS-inducing bench-stepping exercise. Muscle soreness was assessed at baseline, 24, 48, 72, 96, and 120 hours after bench-stepping using a Visual Analog Scale (VAS). Groups were also compared on body awareness (BA), flexibility using the sit-and-reach test (SR), and perceived exertion (RPE). Statistical significance was accepted at p </= 0.05. A 2 x 2 mixed factorial ANOVA with repeated measures at 24 and 48 hours revealed a significant (p < 0.05) group main effect with VAS scores greater for CON than YT. Paired t-tests revealed that in YT, VAS scores were higher before yoga class than after yoga class at 24 hours (21.4 [+/- 6.9] mm vs. 11.1 [+/- 4.1] mm; p = 0.02). The SR was greater in YT than in CON (65.0 [+/- 7.9] cm vs. 33.3 [+/- 7.0] cm; p < 0.01); however, no differences were found between yoga and control in BA (94.0 [+/- 4.4] units vs. 83.8 [+/- 3.7] units; p = 0.21) or in RPE at 5-minute intervals (2.9 [+/- 0.3], 5.3 [+/- 0.8], 5.8 [+/- 0.9], and 5.2 [+/- 0.8] vs. 2.5 [+/- 0.3], 4.0 [+/- 0.5], 4.2 [+/- 0.3], and 4.9 [+/- 0.4]. Yoga training and a single bout of yoga appear to attenuate peak muscle soreness in women following a bout of eccentric exercise. These findings have significant implications for coaches, athletes, and the exercising public who may want to implement yoga training as a preseason regimen or supplemental activity to lessen the symptoms associated with muscle soreness.
PMID: 15574074 [PubMed - in process]
..For nå er DOMS vitenskaplig påvist, he-he:J Physiol. 2005 Jan 27; [Epub ahead of print] Related Articles, Links
Muscular mechanical hyperalgesia revealed by behavioural pain test and c-Fos expression in the spinal dorsal horn after eccentric contraction in rats.
Taguchi T, Matsuda T, Tamura R, Sato J, Mizumura K.
Department of Neural Regulation, Research Institute of Environmental Medicine, Nagoya University.
Delayed onset muscle soreness (DOMS) is quite common, but the mechanism for this phenomenon is still not understood; even the existence of muscle tenderness (mechanical hyperalgesia) has not been demonstrated in experimental models. We developed an animal model of DOMS by inducing eccentric contraction (lengthening contraction, ECC) to the extensor digitorum longus muscle (EDL), and investigated the existence of mechanical hyperalgesia in the EDL by means of behavioural pain tests (Randall-Selitto test and von Frey hair test, applied to/through the skin on the EDL muscle) and c-Fos expression in the spinal dorsal horn. We found that the mechanical withdrawal threshold measured with Randall-Selitto apparatus decreased significantly between 1 and 3 days after ECC, while that measured by von Frey hairs did not. The group that underwent stretching of the muscle only (SHAM group) showed no change in mechanical pain threshold in either test. These results demonstrated that the pain threshold of deep tissues (possibly of the muscle) decreased after ECC. C-Fos immunoreactivity in the dorsal horn (examined 2 days after ECC/SHAM exercise) was not changed by either ECC or compression (1568 mN) to the EDL muscle by itself, but it was significantly increased by applying compression to the EDL muscle 2 days after ECC. This increase was observed in the superficial dorsal horn of the L4 segment of the ipsilateral side, and clearly suppressed by morphine treatment (10 mg/kg, i.p.). These results demonstrated the existence of mechanical hyperalgesia in the muscle subjected to ECC. This model may serve as a model for future study of the neural mechanism of muscle soreness.
PMID: 15677691 [PubMed - as supplied by publisher]
Denne type målinger hadde det vært interessant om de gjorde i et lengre tidsperspektiv, gjerne i et program med benkpress, knebøy og andre sammensatte øvelser:
Hum Mov Sci. 2004 Oct;23(3-4):365-78. Related Articles, Links
Force matching errors following eccentric exercise.
Proske U, Gregory JE, Morgan DL, Percival P, Weerakkody NS, Canny BJ.
Department of Physiology, Monash University, PO Box 13F, Clayton, VIC 3800, Australia.
uwe.proske@med.monash.edu.auDuring eccentric exercise contracting muscles are forcibly lengthened, to act as a brake to control motion of the body. A consequence of eccentric exercise is damage to muscle fibres. It has been reported that following the damage there is disturbance to proprioception, in particular, the senses of force and limb position. Force sense was tested in an isometric force-matching task using the elbow flexor muscles of both arms before and after the muscles in one arm had performed 50 eccentric contractions at a strength of 30% of a maximum voluntary contraction (MVC). The exercise led to an immediate reduction of about 40%, in the force generated during an MVC followed by a slow recovery over the next four days, and to the development of delayed onset muscle soreness (DOMS) lasting about the same time. After the exercise, even though participants believed they were making an accurate match, they made large matching errors, in a direction where the exercised arm developed less force than the unexercised arm. This was true whichever arm was used to generate the reference forces, which were in a range of 5-30% of the reference arm's MVC, with visual feedback of the reference arm's force levels provided to the participant. The errors were correlated with the fall in MVC following the exercise, suggesting that participants were not matching force, but the subjective effort needed to generate the force: the same effort producing less force in a muscle weakened by eccentric exercise. The errors were, however, larger than predicted from the measured reduction in MVC, suggesting that factors other than effort might also be contributing. One factor may be DOMS. To test this idea, force matches were done in the presence of pain, induced in unexercised muscles by injection of hypertonic (5%) saline or by the application of noxious heat to the skin over the muscle. Both procedures led to errors in the same direction as those seen after eccentric exercise.
PMID: 15541523 [PubMed - in process]