Jeg tror de fleste inntar proteinshake som del av et vanlig kosthold, i hvert fall tillater jeg meg å anta det...
De fleste proteintilskudd på markedet er basert på myse, kasein eller en kombinasjon. Aminosyreprofilen for melkeproteiner ansees for å være komplett, enten man bruker BV eller den nyeste PDCAAS som måleenhet, så jeg må spørre på hva slags grunnlag du kan si at det ikke er fullverdig?
Din påstand om at økt proteininntak er skadelig eller på annen måte svekker nyrefunksjonen hos normale, friske mennesker vil jeg også gjerne se en referanse på. Det lille jeg har sett av studier ser faktisk heller ut til å indikere at filtreringsfunksjon og -rate STYRKES når man inntar mer protein, men her har de vel kun sett på inntak opptil 1.5g/kg/dag. Nå må man jo også se på det faktum at millioner av kroppsbyggere, fitnessutøvere og idrettsutøvere i mange år har hatt proteininntak i området 3-5g/kg/dag - og antall rapporterte/dokumenterte nyreskader som følge av dette? Veldig få eller ingen som jeg vet om...
Til og med hos pasienter med svekket nyrefunksjon har anbefalingene om en lav-proteindiett blitt revurdert i senere år, samt hvorvidt det gjelder alle typer protein (animalsk protein ser ut til å være verre enn f.eks. melkebasert protein).
J Am Diet Assoc. 2007 Apr;107(4):644-50.
Are high-protein, vegetable-based diets safe for kidney function? A review of the literature.
* Bernstein AM,
* Treyzon L,
* Li Z.
In individuals with chronic kidney disease, high-protein diets have been shown to accelerate renal deterioration, whereas low-protein diets increase the risk of protein malnutrition. Vegetarian diets have been promoted as a way to halt progression of kidney disease while maintaining adequate nutrition. We review the literature to date comparing the effects of animal and vegetable protein on kidney function in health and disease. Diets with conventional amounts of protein, as well as high-protein diets, are reviewed. The literature shows that in short-term clinical trials, animal protein causes dynamic effects on renal function, whereas egg white, dairy, and soy do not. These differences are seen both in diets with conventional amounts of protein and those with high amounts of protein. The long-term effects of animal protein on normal kidney function are not known. Although data on persons with chronic kidney disease are limited, it appears that high intake of animal and vegetable proteins accelerates the underlying disease process not only in physiologic studies but also in short-term interventional trials. The long-term effects of high protein intake on chronic kidney disease are still poorly understood. Several mechanisms have been suggested to explain the different effects of animal and vegetable proteins on normal kidney function, including differences in postprandial circulating hormones, sites of protein metabolism, and interaction with accompanying micronutrients.
Nephrology (Carlton). 2006 Feb;11(1):58-62.
Dietary protein restriction as a treatment for slowing chronic kidney disease progression: the case against.
Johnson DW.
Department of Renal Medicine, University of Queensland at Princess Alexandra Hospital, Brisbane, Australia.
david_johnson@health.qld.gov.auLow-protein diets (<or=0.7 g/kg per day) have been advocated for over 70 years as a means of slowing the rate of progression of kidney disease and delaying the appearance of uraemic symptoms and need for dialysis. However, the available evidence to date suggests that the benefit : risk ratio of dietary protein restriction is not favourable in that: (i) compliance is generally sub-optimal; (ii) most of the published randomised controlled trials demonstrate that low-protein diets do not significantly slow the rate of kidney disease progression; (iii) meta-analyses of controlled trials have demonstrated strong evidence of publication bias favouring studies with positive, rather than negative, results; (iv) the optimal level and duration of dietary protein intake have not been defined; (v) there is no convincing clinical evidence that dietary protein restriction provides any benefit beyond that afforded by angiotensin blockade; and (vi) low-protein diets are associated with both statistically and clinically significant declines in nutritional markers in chronic kidney disease populations, which already have a high prevalence of malnutrition. Patients with progressive kidney disease are therefore likely to be better served by avoiding dietary protein restriction (thereby ensuring optimal preservation of their nutrition) and instituting alternative, proven renoprotective measures (e.g. renin-angiotensin system blockade, blood pressure reduction and statin therapy).